Preservative- free options include the I- LID N LASH PLUS wipes and NACLINO Lid Wipes. doxycycline weight gain 52, 59 The risk of major complications is difficult to ascertain given a paucity of literature focused directly on STS and polidocanol treatment of VMs, although rare occurrences of anaphylaxis 60 and cardiovascular deterioration 61, 62 have occurred with both.